#  Martin Pačesa and Santi Bhattarai-Kline  

 



####  calendar\_today Date and Time 

 **November 21, 2022** 

 01:00PM - 02:00PM EST 

 



 

   ![mp_headshot2022.jpg](/sites/g/files/omnuum4021/files/styles/hwp_1_1__360x360_scale/public/genome-engineering-seminar-series/files/mp_headshot2022.jpg?itok=osO1_P3O) 

 

 **Martin Pačesa,** [Jinek Lab](https://www.bioc.uzh.ch/en/research/research-groups/jinek/), University of Zurich

 Target-induced conformational activation and mismatch tolerance of CRISPR-Cas9

 [Nature (2022)](https://www.nature.com/articles/s41586-022-05114-0) and [Cell (2022)](https://www.cell.com/cell/fulltext/S0092-8674(22)01198-9)

   ![headshot_2022.jpg](/sites/g/files/omnuum4021/files/styles/hwp_1_1__360x360_scale/public/genome-engineering-seminar-series/files/headshot_2022.jpg?itok=YBYN2Qr6) 

 

**Santi Bhattarai-Kline,** [Shipman Lab](https://www.shipmanlab.org/), Gladstone Institute of Data Science and Biotechnology, San Francisco. [Recording gene expression order in DNA by CRISPR addition of retron barcodes](https://www.nature.com/articles/s41586-022-04994-6)

 Nature (2022)

 **Recording:** [https://harvard.zoom.us/rec/share/7dz2rSmU9sIesGXZT9fmIaZbwZ2kJU\_fU9u4IIQ6Cm-mLchekK-DmiDi-0OB6qcj.sVKebVh9prIa9LOz](https://harvard.zoom.us/rec/share/7dz2rSmU9sIesGXZT9fmIaZbwZ2kJU_fU9u4IIQ6Cm-mLchekK-DmiDi-0OB6qcj.sVKebVh9prIa9LOz)



 

 



 

 

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