https://harvard.zoom.us/j/94394339529

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Weekly: https://harvard.zoom.us/webinar/tJAufu2rrTIvGN0GtDMl4oxdGIJ1K_DsLcZ_/ics...
Topic: Genome Engineering Seminar Series at HMS

Please click the link below to join the webinar:
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Meeting ID: 943 9433 9529
SIP: 94394339529@zoomcrc.com

 

Resources

CRISPRpedia: https://innovativegenomics.org/crisprpedia/

Genome Writers Guild: https://www.genomewritersguild.org/

CRISPR Medicine News https://crisprmedicinenews.com/  

Addgene technical tips and reagents: https://www.addgene.org/genome-engineering/

Educational materials at IGI: https://innovativegenomics.org/education/digital-resources/

(feel free to make suggestions to: genomeengineeringseminarshms@gmail.com)

When is it?
-Mondays 1pm-2pm EST via zoom.
 
What is the format?
-Zoom webinar, 1hr meeting.
-30min each presenter (20min presentation + 10min questions).
-Group/shared presentations are still 30min total
-Attendees ask questions using the zoom Q&A function

What is the zoom link?
https://harvard.zoom.us/j/94394339529

Who presents?
-First authors of recent (<1yr) genome engineering papers or manuscripts

Can I attend?
-Yes, anyone in the world is welcome to attend the meetings.

I'm not affiliated with Harvard Medical School, can I attend?
-Yes, anyone in the world is welcome to attend the meetings.

Do I need experience in genome engineering to attend?
-No, attendees can have any level of expertise in genome engineering (beginners are welcome).

Who attends these meetings?
-Attendees have a wide spectrum of interests, scientific backgrounds, and career positions, ranging from undergrads, technicians, grad students, post-docs, principal investigators, etc.

How can I receive announcements of upcoming speakers?
-Join our mailing list.

Are the talks recorded?
-If speakers consent, the recordings will be available as a link on our website within 1 week. See the "Past seminars" tab.

Can I share the zoom link with others?
-Yes, please distribute information about our seminar series to anyone you think is interested.

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Past Seminar Schedule

2022 Nov 28

Break-no talks

Date: 

Monday, November 28, 2022, 1:00pm to 2:00pm

2022 Nov 21

Martin Pačesa and Santi Bhattarai-Kline

Date: 

Monday, November 21, 2022, 1:00pm to 2:00pm

Martin Pačesa, Jinek Lab, University of Zurich

Target-induced conformational activation and mismatch tolerance of CRISPR-Cas9

Nature (2022) and Cell (2022)

 

 

Santi Bhattarai-Kline, Shipman Lab, Gladstone Institute of Data Science and Biotechnology, San Francisco.

Recording gene expression order in DNA by CRISPR addition of retron barcodes

Nature (2022)

 

 

Recording: https://harvard.zoom.us/rec/share/7dz2rSmU9sIesGXZT9fmIaZbwZ2kJU_fU9u4IIQ6Cm-mLchekK-DmiDi-0OB6qcj.sVKebVh9prIa9LOz 

 

2022 Nov 14

Break - no talks

Date: 

Monday, November 14, 2022, 1:00pm to 2:00pm

2022 Nov 07

Zhixin Lei and Sung-Ik Cho

Date: 

Monday, November 7, 2022, 1:00pm to 2:00pm

zhixin_lei

 

Zhixin Lei, Chengqi Yi Lab. Peking-Tsinghua Center for Life Sciences, Peking University.

Mitochondrial base editor induces substantial nuclear off-target mutations

Nature (2022)

 

 

  

 

Sung-Ik Cho, Kim Lab. Seoul National University, Seoul.

Targeted A-to-G base editing in human mitochondrial DNA with programmable deaminases

Cell (2022)

 

 

 

Recording: https://harvard.zoom.us/rec/share/xKyymvx0QRa0fxS02LpTnzktdkc9eq3hlYXE9XsRM8JYcIw96tS0dOFn6jtTN2lf.DkBRfJG7i8pVJaOn 

2022 Oct 31
2022 Oct 24

Minja Velimirovic and Chunyi Hu & Sam van Beljouw

Date: 

Monday, October 24, 2022, 1:00pm to 2:00pm

   

Minja VelimirovicSherwood Lab, Brigham and Women's Hospital, Harvard Medical School

Peptide fusion improves prime editing efficiency

Nature Communications (2022)

 


      

      Chunyi Hu & Sam van BeljouwKe Lab. Cornell University

      Craspase is a CRISPR RNA-guided, RNA-activated protease.

      Science (2022)

 

 

Recording: https://harvard.zoom.us/rec/share/7bUbjrl03TU7ciZ9p7-l3T5N9JobYzsqFymuZn...

2022 Oct 17

Alena Bishop and Qichen Yuan

Date: 

Monday, October 17, 2022, 1:00pm to 2:00pm

       Alena Bishop, Gantz Lab. University of California San Diego

       Double-tap gene drive uses iterative genome targeting to help overcome resistance alleles

       Nature Communications (2022)

 

 

      Qichen Yuan, Gao Lab. Rice University, Houston 

      Multiplex base- and prime-editing with drive-and-process CRISPR arrays

      Nature Communications (2022)

 

 

 

Recording: https://harvard.zoom.us/rec/share/WbzFRFdD0aL0nkS78pDmMNE3zap9YCHJa3hqw1...

 

2022 Oct 03

Eric Aird and Vivasvan S. Vykunta

Date: 

Monday, October 3, 2022, 1:00pm to 2:00pm

         

          Eric Aird, Corn Lab, ETH Zurich

          Recursive Editing improves homology-directed repair through retargeting of undesired outcomes

          Nature Communications (2022)

 

          Vivasvan S. Vykunta, Marson Lab, Gladstone-UCSF Institute of Genomic Immunology.

          University of California San Francisco.  

          High-yield genome engineering in primary cells using a hybrid ssDNA repair

          template and small-molecule cocktails

          Nature Biotechnology (2022)

 

Recording: https://harvard.zoom.us/rec/share/jyzJNuMpwAew4wvWDjPK1Mab5VEDim9PQUvfZ8tIXVnSbeJcdLP_TCx0KTV-DKHJ.KTkoEbvRzearE84o 

2022 Sep 26
2022 Sep 19
2022 Sep 12
2022 Apr 18
2022 Apr 11
2022 Apr 04
2022 Mar 28

Break

Date: 

Monday, March 28, 2022, 1:00pm to 2:00pm

2022 Mar 21
2022 Mar 07
2022 Feb 28

Courtney Carlson and Aditya Raguram and Samagya Banskota

Date: 

Monday, February 28, 2022, 1:00pm to 2:00pm

courtney1

 

 

Courtney Carlson, Chang Liu lab, Department of Biomedical Engineering, UC Irvine

Molecular recording of sequential cellular events into DNA, biorxiv, 2021

 

aditya and samagya-banskota

 

Aditya Raguram and Samagya Banskota, David Liu Lab, Harvard University and Broad Institute, Boston, United States. 

Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins. Cell. 2022

 

Recordinghttps://harvard.zoom.us/rec/share/axCVJXoQ-uoDkUoVZIWcj4akvcvX-CiJ-XSZ2A...

2022 Feb 14
2022 Feb 07
2022 Jan 24
2021 Nov 29

No seminar

Date: 

Monday, November 29, 2021, 1:00pm to 2:00pm

No seminar
2021 Nov 22

Junhong Choi and Jens Magnusson

Date: 

Monday, November 22, 2021, 1:00pm to 2:00pm

Choi

 

Junhong Choi, Shendure Lab, University of Washington, Seattle, USA.

Precise genomic deletions using paired prime editing Nature Biotechnology 2021

 

 

Jens

 

Jens Magnusson, Qi Lab, Standford University, USA.

Enhanced Cas12a multi-gene regulation using a CRISPR array separator. Elife 2021

 

 

Recordinghttps://harvard.zoom.us/rec/share/9AlOLdYxfr5ARpM0ONqHrO3YNSj8FPrsSyyUDPGDrYFH6K8LaR3y4_Zg2lfR42cw.tECHW0JRlD0hWFB5

2021 Nov 15

Ahsen Özcan and Peter Chen

Date: 

Monday, November 15, 2021, 1:00pm to 2:00pm

ahsenf

 

Ahsen ÖzcanAbudayyeh-Gootenberg lab, McGovern Institute for Brain Research at MIT, Cambridge, MA, USA

Programmable RNA targeting with the single-protein CRISPR effector Cas7-11. Nature (2021).
 

 

peter chen

 

Peter Chen, Liu Lab, Harvard University and Broad Institute, Boston, United States.

Enhanced prime editing systems by manipulating cellular determinants of editing outcomes. Cell 2021

 

 

 

Recordinghttps://harvard.zoom.us/rec/share/NQZz5KInHt1HdXSGSpqloYECvKZR2tfNtMuMGTcHy0t8aG6OGi7HOk5D2FO4RHQ.yrqSSemZkSFji3Ea

2021 Nov 08

Weiting Zhang and Doyon Kim

Date: 

Monday, November 8, 2021, 1:00pm to 2:00pm

Weiting Zhang

 

 

Weiting Zhang, Yeh Lab, Massachusetts General Hospital, Boston, United States.

CRISPR prime editing with ribonucleoprotein complexes in zebrafish and primary human cells. Nature Biotechnol 2021.

 
 
 
 
 
Doyon Kim
Doyon Kim, Kim Lab, Genome Editing Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea
 
 
 
 
 
 
 
More

Upcoming Seminar Schedule

2022 Dec 12

Florian Schmidt, Jakob Zimmermann, Tanmay Tanna and Monica Neugebauer

Date: 

Monday, December 12, 2022, 1:00pm to 2:00pm

Florian Schmidt, Jakob Zimmermann, Tanmay Tanna, Platt Lab and Macpherson Lab.  ETH Zurich and Bern University

Noninvasive assessment of gut function using transcriptional recording sentinel cells

Science (2022)

 

Monica Neugebauer, Liu Lab. Broad Institute of MIT and Harvard.

Evolution of an adenine base editor into a small, efficient cytosine base editor with low off-target activity

Nature Biotechnology (2022)

 

2022 Dec 19

Matthew Durrant, Alison Fanton, Josh Tycko and Liang Chen

Date: 

Monday, December 19, 2022, 1:00pm to 2:00pm

Matthew Durrant, Alison Fanton, Hsu Lab, Arc Institute and University of California, Berkeley

Josh Tycko, Bintu Lab, Stanford University

Systematic discovery of recombinases for efficient integration of large DNA sequences into the human genome. Nature Biotechnology (2022)

 

Liang Chen, Dali Li Lab. School of Life Sciences, East China Normal University

Re-engineering the adenine deaminase TadA-8e for efficient and specific CRISPR-based cytosine base editing

Nature Biotechnology (2022)

 

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