Past Events

Alejandro Delgado & Wells Burrell

May 18, 2026

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1:00PM - 2:15PM EDT

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https://harvard.zoom.us/j/94394339529

Virtual

Wells Burrell ( Sanjana Lab, NY Genome) Rational design of synthetic proteins using a genome-scale CRISPR screen Biorxiv, 2026 Alejandro Delgado ( Shipman Lab, UCSF) Genome editing of phylogenetically distinct bacteria using cross-species retron-mediated...

Alison Fanton & Luca Biasco

April 6, 2026

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1:00PM - 2:10PM EDT

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https://harvard.zoom.us/j/94394339529

Virtual

Alison Fanton ( Hsu lab, Arc Institute) Site-specific DNA insertion into the human genome with engineered recombinases Nature Biotechnology, 2026 Luca Biasco (University College London) In vivo gene editing of human hematopoietic stem and progenitor cells...

Saeko Ishida & Oana Pelea

March 2, 2026

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1:00PM - 2:00PM EST

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https://harvard.zoom.us/j/94394339529

Other

Saeko Ishida ( Mashimo Lab, U. of Tokyo) CRISPR–Cas3-based editing for targeted deletions in a mouse model of transthyretin amyloidosis Nature Biotechnology, 2026 Oana Pelea ( Jinek Lab, U. of Zurich) Programmable genome editing in human cells using RNA...

Ramiro Perrotta and Noah Robinson

February 9, 2026

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1:00PM - 2:00PM EST

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https://harvard.zoom.us/j/94394339529

Virtual

Ramiro Perrotta ( Church Lab, HMS) Engineered base editors with reduced bystander editing through directed evolution Nature Biotechnology, 2025 Noah Robinson ( Wang Lab, Caltech) Construction of complex and diverse DNA sequences using DNA three-way...

Connor Tou and Isabell Kassing

December 1, 2025

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1:00PM - 2:00PM EST

In Person

Connor Tou ( Kleinstiver Lab) Immune evasive DNA donors and recombinases license kilobase-scale genome writing 2025 Isabell Kassing ( Wagner Lab) Versatile and efficient non-viral integration of large transgenes in human T cells via CRISPR knock-in and...

Sébastien Levesque & Bin Liu

November 17, 2025

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1:00PM - 2:00PM EST

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https://harvard.zoom.us/j/94394339529

Virtual

Sébastien Levesque ( Bauer Lab, Boston Children's Hospital) In cellulo DNA assembly for targeted genomic integration and rearrangement in human cells Biorxiv, 2025 Bin Liu ( Sontheimer Lab, UMass Chan Medical School) Prime assembly with linear DNA donors...

Josh Tycko and Sarah Pierce

November 3, 2025

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1:00PM - 2:00PM EST

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https://harvard.zoom.us/j/94394339529

In Person

Josh Tycko ( Bassik Lab) Development of compact transcriptional effectors using high-throughput measurements in diverse contexts Nature Biotechnology, 2025 Sarah Pierce ( Liu Lab) Prime editing-installed suppressor tRNAs for disease-agnostic genome...

Monday, October 20th, 2025: Alex Sousa & Vikash Chauhan

October 20, 2025

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1:00PM - 2:00PM EDT

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https://harvard.zoom.us/j/94394339529

Virtual

Alex Sousa ( Liu Lab , Broad Institute) In vivo prime editing rescues alternating hemiplegia of childhood in mice Cell (2025) Vikash Chauhan ( Langer Lab , MIT) Engineered prime editors with minimal genomic errors Nature (2025) Recording: https://harvard...

Monday, October 6th, 2025: Katie Yost & Chengtao Xu

October 6, 2025

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1:00PM - 2:00PM EDT

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https://harvard.zoom.us/j/94394339529

Virtual

Katie Yost ( Weissman Lab, MIT) High-resolution spatial mapping of cell state and lineage dynamics in vivo with PEtracer Science (2025) Chengtao Xu ( Ke Lab, Yale) Conversion of IscB and Cas9 into RNA-guided RNA editors Cell (2025) Recording: https:/...

Xiaoxue Zhang, Christopher Fell, Lukas Villiger & Isaac Witte

May 19, 2025

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1:00PM - 2:15PM EDT

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https://harvard.zoom.us/j/94394339529

Virtual

Note: 3 talks!!! Xiaoxue Zhang ( Wei Lab, Peking University) Precise modelling of mitochondrial diseases using optimized mitoBEs Nature, 2025 Christopher Fell & Lukas Villiger ( AbuGoot Lab, Brigham & Women's Hospital) Reprogramming site-specific...

Julian Geilenkeuser, Niklas Armbrust & Rachel Silverstein

May 12, 2025

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1:00PM - 2:00PM EDT

Virtual

Julian Geilenkeuser & Niklas Armbrust (Truong Lab, Institute for Synthetic Biomedicine, Helmholtz Munich) Engineered nucleocytosolic vehicles for loading of programmable editors Cell, 2025 Rachel Silverstein ( Kleinstiver Lab, MGH) Custom CRISPR—Cas9 PAM...

Monday, April 28th, 1 PM EST: GESS Special Seminar: Focus on HSC Gene Editing

April 28, 2025

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1:00PM - 2:00PM EDT

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https://harvard.zoom.us/j/94394339529

Virtual

Jing Zheng, ( Dan Bauer Lab , Boston Children’s Hospital) Gene editing without ex vivo culture evades genotoxicity in human hematopoietic stem cells Cell Stem Cell, 2025 Selami Demirci ( Tisdale Lab ,NIH NHLBI) BCL11A +58/+55 enhancer-editing facilitates...